Understanding Regenerative Skin Treatments: How PRP and PRF Differ

Woman lies with eyes closed, awaiting her PRP/PRF treatment at her medspa

At Cisne Wellness, our patients enjoy personalized treatments designed to enhance natural beauty using the body’s own healing abilities.

Among our most requested options are PRP and PRF. Both are advanced regenerative therapies that promote collagen growth, improve skin texture, and help restore volume naturally.

Although they share many benefits, these two treatments differ in preparation and how they release growth factors to rejuvenate your skin.

Administered by our injection experts, platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) can both help achieve results that look refreshed and balanced, never overdone. Here’s how each works and how they’re different.

What Is PRP?

PRP uses a small sample of your own blood to separate the platelet-rich layer through a quick centrifugation process. The resulting plasma is rich in growth factors and proteins. These substances stimulate collagen production and cellular renewal.

When injected or used in combination with microneedling, PRP encourages smoother, firmer, and more radiant skin.

Because PRP is spun at a high speed during centrifugation, it isolates platelets quickly, producing a powerful serum that works well for boosting glow, improving fine lines, and supporting healing after laser treatments. It’s ideal for patients looking for noticeable rejuvenation with minimal downtime.

What Is PRF?

PRF, or Platelet-Rich Fibrin, is a newer generation of platelet therapy that is prepared using a slower spin. This gentle process allows more platelets, stem cells, and white blood cells to remain suspended in a fibrin matrix — a soft, natural scaffold that gradually releases growth factors over time.

This slower release helps sustain results longer and encourages continued collagen stimulation.

PRF works beautifully for patients seeking natural volume restoration, under-eye rejuvenation, or overall skin tightening. Because PRF doesn’t contain additives or anticoagulants, it’s considered one of the most natural regenerative options available.

Choosing Between PRP and PRF

Both PRP and PRF support healthier, more youthful skin, but each offers unique advantages. PRP provides an immediate radiance boost, while PRF offers a more gradual, long-lasting enhancement. Many patients benefit from combining both therapies over time to achieve comprehensive results tailored to their goals.

Book Your PRP or PRF Consultation in Lakeland, FL

Our expert team at Cisne Wellness understands that every face tells a story, and we believe that every treatment plan should be as individual as you are. Whether you’re seeking subtle rejuvenation, refined balance, or improved skin quality, our personalized approach ensures your results feel naturally yours. If you’re ready to learn how PRP and PRF can rejuvenate your skin from within, call Cisne Wellness at 863-825-2005 to book your consultation with our regenerative skin treatment experts.

How Can We Help?

* All indicated fields must be completed.
Please include non-medical questions and correspondence only.

Monday, Tuesday, Wednesday: 9am - 5pm
Thursday: 9am - 6pm
Friday: 8am - 4pm
Saturday: 9am - 2 pm

Accessibility Toolbar

November & Holiday Specials
Close the CTA